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Connectivity differences between groups. Top: right insula showing lower connectivity with the salience network in the ≥2 AD group compared to the 1 AD group (Z = 3.86, p = .007 FDR corrected on cluster-level). Figure displays cluster with initial threshold of p < .001 uncorrected. Bottom: Parameter estimates averaged across total insula cluster and 90% confidence intervals showing decreased connectivity of the insula within the salience network in the ≥2 AD group.
