Table 1.
PCa miR | Expression (PCa versus Control) | Target | References |
---|---|---|---|
hsa-let-7c | down | MYC, RAS, HMGA2 | 47,48 |
hsa-miR-21 | up | MARKS, PDCD4, TPM1 | 83 |
hsa-miR-32 | up | BTG2 | 84 |
hsa-miR-34a | down | CD44, Cyclin D1, CDK4, CDK6, c-MET, ZEB1 | 85,86 |
hsa-miR-96 | up | RAD51, REV1 | 87 |
hsa-miR-100 | down | MYC, Oct4, KLF4 | 88 |
hsa-miR-105 | down | CDK6 | 89 |
hsa-miR-124 | down | TLN1 | 90 |
hsa-miR-125b | up | EIF4EBP1, p14ARF | 91 |
hsa-miR-130b | down | MMP2 | 92 |
hsa-miR-133b | down | EGFR | 93 |
hsa-miR-141 | up | SHP | 94 |
hsa-miR-143 | down | GOLM1 | 95 |
hsa-miR-146a | down | Rac1 | 96 |
hsa-miR-153 | up | PTEN, FOXO1 | 97 |
hsa-miR-154 | down | CCND2 | 98 |
hsa-miR-155 | down | STAT3 | 99 |
hsa-miR-181b | up | MLK2 | 100 |
hsa-miR-181c | up | DAX-1 | 101 |
hsa-miR-181d | up | DAX-1 | 101 |
hsa-miR-182 | up | NDRG1 | 102 |
hsa-miR-183 | up | DKK-3, SMAD4 | 103 |
hsa-miR-187 | down | ALDH1A3 | 104 |
hsa-miR-200b | down | ZEB1, ZEB2 | 105 |
MARKS, myristoylated alanine-rich protein kinase C substrate; MMP, matrix metalloproteinase; NDRG1, N-myc downstream regulated gene 1; PTEN, phosphatase and tensin homolog; SHP, small heterodimer partner; TLN1, talin 1; TPM1, tropomyosin 1; ZEB, zinc-finger E-box binding homeobox.