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. 2019 Nov 22;10:1434. doi: 10.3389/fphys.2019.01434

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Copyright © 2019 Shi, Yuan, Wang, Wang, Liu, Tian, Guo, Zhang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Higher nocturnal and diurnal arterial pressure in TASK^−/− mice. Telemetric recordings of arterial pressure and HR were made over 24 h in TASK^+/+ and TASK^−/− mice. Nocturnal BP and HR were calculated based on measurements made from 7 pm to 7 am, so 7 am to 7 pm for diurnal BP and HR. The average nocturnal SBP (A) and DBP (C), diurnal SBP (B) and DBP (D) were higher in TASK^−/− mice than control mice. The average nocturnal (E) and diurnal (F) HR was similar between two genotypes. n = 13 mice for each genotype, ^***p < 0.001, ^****p < 0.0001 as indicated by unpaired t test.