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. 2019 Nov 22;9:1250. doi: 10.3389/fonc.2019.01250

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Copyright © 2019 Wu, Zhang, Zhao, Liu, Chen, Li, Wu, Li, Guo and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decision curves for radiomics models in training (A), validation (B), and testing sets (C). The grey reference line indicates the assumption that all patients are diagnosed to be MSI CRC; black dashed reference line indicates the assumption that all patients are diagnosed to be MSS CRC. In training, validation, testing sets, the net benefit is 17.44, 15.40, and 13.43, respectively. A larger area under the decision curve indicates a better clinical utility. MSI, microsatellite instability; CRC, colorectal cancer; MSS, microsatellite stability.