Table 1.

Intraductal injection of ethanol delays onset of tumor formation

		Non-injected vs. non-injected glands			Non-injected vs. injected glands
Animal groups	Animals (n)	Latency (days)	Glands (n)	p value	Latency (days)	Glands (n)	p value
Untreated vs. not injected	25 vs. 10	150 vs. 169	250 vs. 100	0.4279	n/a	n/a	n/a
Untreated vs. PBS-injected	25 vs. 10	150 vs. 161	250 vs. 43	0.9110	150 vs. 148	250 vs. 57	0.6570
Untreated vs. 50% EtOH-injecteda	25 vs. 6	150 vs. 184	250 vs. 36	0.0366	150 vs. 198	250 vs. 24	0.0049
Untreated vs. 70% EtOH-injecteda	25 vs. 11	150 vs. 178	250 vs. 58	0.0151	150 vs. 207	250 vs. 52	< 0.0001
Untreated vs. 70% EtOH-injectedb	25 vs. 13	150 vs. 176.5	250 vs. 35	0.0059	150 vs. 217	250 vs. 95	< 0.0001
Within PBS-injected	10	n/a	n/a	n/a	161 vs. 148	43 vs. 57	0.7274
Within 50% EtOH-injecteda	6	n/a	n/a	n/a	184 vs. 198	36 vs. 24	0.2987
Within 70% EtOH-injecteda	11	n/a	n/a	n/a	178 vs. 207	58 vs. 52	0.0002
Within 70% EtOH-injectedb	13	n/a	n/a	n/a	176.5 vs. 217	35 vs. 95	0.0006

Median latency in days of age is provided for indicated animal treatment group or mammary gland treatment class. p values were calculated by the log-rank test (Mantel-Cox) comparing tumor-free survival between indicated treatment groups or classes (reference vs. test). ^aEtOH was diluted in sterile PBS with iodine-containing contrast agent. ^bEtOH was diluted in sterile water