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. 2019 Nov 22;9:1310. doi: 10.3389/fonc.2019.01310

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Copyright © 2019 Deng, Lin, Chen, Zhang, Xu, Yang, Shen, Yang, Lu, Sheng, Yin, Zhang and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identified IDH1-associated immune genes. (A) Genomic landscape of LGG and the mutational signatures in the TCGA dataset, which were assayed on the FireBrowse platform. (B) Volcano plot of 984 genes differentially expressed between IDH1^wt and IDH1^mut patients. (C) Heatmap of genes differentially expressed between IDH1^wt and IDH1^mut patients. (D) Heatmap of immune genes differentially expressed between IDH1^wt and IDH1^mut patients.