Table 3.
Arm A | Arm B | Total | P value | ||||
---|---|---|---|---|---|---|---|
No. | % | No. | % | No. | % | ||
Type of surgery | |||||||
Miles | 36 | 67.90% | 32 | 56.10% | 68 | 61.80% | |
Anterior resection | 13 | 24.50% | 22 | 38.60% | 35 | 31.80% | |
Hartmann | 4 | 7.50% | 3 | 5.30% | 7 | 6.40% | 0.279 |
ypT stage | |||||||
ypT0 | 10 | 18.90% | 16 | 28.10% | 26 | 23.60% | |
ypT1–2 | 16 | 30.20% | 24 | 42.10% | 40 | 36.40% | |
ypT3–4 | 27 | 50.90% | 17 | 29.80% | 44 | 40.00% | 0.077 |
ypN stage | |||||||
N0 | 29 | 54.70% | 39 | 68.40% | 68 | 61.80% | |
N+ | 24 | 45.30% | 18 | 31.60% | 42 | 38.20% | 0.139 |
pCR | |||||||
pCR | 8 | 15.10% | 14 | 24.60% | 22 | 20.00% | |
non-pCR | 45 | 84.90% | 43 | 75.40% | 88 | 80.00% | 0.215 |
Total | 53 | 57 | 110 |
Arm A, 5 weeks of treatment with radiotherapy 50 Gy/25 fractions with concurrent capecitabine 625 mg/m2 twice daily 5 days per week and oxaliplatin 50 mg/m2 once weekly; Arm B, 5 weeks of treatment with radiotherapy 55 Gy/25 fractions with concurrent capecitabine 625 mg/m2 twice daily 5 days per week and oxaliplatin 50 mg/m2 once weekly, followed by a cycle of XELOX
Abbreviations: pCR Pathological complete response;aPatients who did not undergo surgery excluded