Table 1.

Subtypes of PDAC based on metabolic features.

Subtype	Metabolic features	Therapeutic strategies
Slow proliferating	Low levels of amino acids and carbohydrates	Glycolytic inhibitors or inhibitors of lipid biosynthesis
Glycolytic	Metabolites elevated in glycolytic and serine pathways, lower levels of metabolites of redox homeostasis	Glycolytic, Gln inhibitors and ROS-inducing agents
Lipogenic	Enriched for lipid metabolites and TCA cycle metabolites	Inhibitors of lipid biosynthesis