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. 2019 Nov 25;12:10099–10105. doi: 10.2147/OTT.S224053

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© 2019 Xu et al.

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PD-L1 expression was up-regulated in cytokine-induced EMT model. (A) Expression of immune-checkpoint inhibitors as Galectine 9, CEACAM1, PD-L1, PD-L2, Vista before and after induction of EMT on SGC7901 cells. (B) The changes in the expression of PD-L1 with TGFβ receptor inhibitor treatment in SGC7901-EMT cells. (D) Expression of PD-L1 mRNA and protein were measured following TGFβ1 treatment by QRT-PCR (C) or ELISA (D). Data are expressed as means ± S.D of three independent experiments, each performed in triplicate. ***P < 0.001.