Table 3.
Antibiotic Susceptibility Pattern Among CAP Associated Pathogens
| Bacteria | AMK, n(%) | GEN, n(%) | AMC, n(%) | SAM, n(%) | TIC, n(%) | PIP, n(%) | CFZ, n(%) | CAZ, n(%) | CTX, n(%) | CRO, n(%) | CFP, n(%) | SXT, n(%) | CIP, n(%) | LVX, n(%) | MXF, n(%) | IPM, n(%) | MEM, n(%) | VAN, n(%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A. baumannii (n=28) | ||||||||||||||||||
| S | 23 (82.1) | 22 (78.6) | 3 (10.7) | 15 (53.6) | 5 (17.9) | 12 (42.9) | 8 (28.6) | 15 (53.6) | 13 (46.4) | 15 (53.6) | 26 (92.9) | 20 (71.4) | 6 (21.4) | 17 (60.7) | 13 (46.4) | 14 (50.0) | 21 (75.0) | NA |
| I | 0 | 1 (3.6) | 0 | 0 | 8 (28.6) | 3 (10.7) | 5 (17.9) | 2 (7.1) | 1 (3.6) | 3 (10.7) | 0 | 0 | 5 (17.9) | 0 | 12 (42.9) | 4 (14.3) | 1 (3.6) | NA |
| R | 5 (17.9) | 5 (17.9) | 25 (89.3) | 13 (46.4) | 15 (53.6) | 13 (46.4) | 15 (53.6) | 11 (39.3) | 14 (50.0) | 10 (35.7) | 2 (7.2) | 8 (28.6) | 17 (60.7) | 11 (39.3) | 3 (10.7) | 10 (35.7) | 6 (21.4) | NA |
| E. coli (n=10) | ||||||||||||||||||
| S | 8 (80.0) | 9 (90.0) | 6 (60.0) | 3 (30.0) | 2 (20.0) | 6 (60.0) | 4 (40.0) | 8 (80.0) | 8 (80.0) | 7 (70.0) | 9 (90.0) | 7 (70.0) | 6 (60.0) | 7 (70.0) | 7 (70.0) | 8 (80.0) | 9 (90.0) | NA |
| I | 0 | 0 | 0 | 2 (20.0) | 2 (20.0) | 0 | 2 (20.0) | 0 | 1 (10.0) | 0 | 0 | 1 (10.0) | 1 (10.0) | 1 (10.0) | 2 (20.0) | 2 (20.0) | 0 | NA |
| R | 2 (20.0) | 1 (10.0) | 4 (40.0) | 5 (50.0) | 6 (60.0) | 4 (40.0) | 4 (40.0) | 2 (20.0) | 1 (10.0) | 3 (30.0) | 1 (10.0) | 2 (20.0) | 3 (30.0) | 2 (20.0) | 1 (10.0) | 0 | 1 (10.0) | NA |
| Enterobacter. spp (n=11) | ||||||||||||||||||
| S | 10 (90.9) | 9 (81.8) | 2 (18.2) | 2 (18.2) | 5 (45.5) | 7 (63.6) | 2 (18.2) | 8 (72.7) | 7 (63.6) | 8 (72.7) | 10 (90.9) | 6 (54.5) | 7 (63.6) | 10 (90.9) | 4 (36.4) | 7 (63.6) | 10 (90.9) | NA |
| I | 0 | 0 | 0 | 0 | 3 (27.3) | 1 (9.1) | 0 | 2 (18.2) | 0 | 0 | 0 | 1 (9.1) | 1 (9.1) | 0 | 5 (45.5) | 2 (18.2) | 0 | NA |
| R | 1 (9.1) | 2 (18.2) | 9 (81.8) | 9 (81.8) | 3 (27.3) | 3 (27.3) | 9 (81.8) | 1 (9.1) | 4 (36.4) | 3 (27.3) | 1 (9.1) | 4 (36.4) | 3 (27.3) | 1 (9.1) | 2 (18.2) | 2 (18.2) | 1 (9.1) | NA |
| K. pneumoniae (n=27) | ||||||||||||||||||
| S | 25 (92.6) | 22 (81.5) | 7 (25.9) | 7 (25.9) | 6 (22.2) | 16 (59.3) | 11 (40.7) | 17 (63.0) | 18 (66.7) | 18 (66.7) | 22 (81.5) | 21 (77.8) | 8 (29.6) | 21 (77.8) | 17 (63.0) | 19 (70.4) | 22 (81.5) | NA |
| I | 0 | 0 | 1 (3.7) | 1 (3.7) | 7 (25.9) | 1 (3.7) | 2 (7.4) | 2 (7.4) | 0 | 0 | 1 (3.7) | 3 (11.1) | 2 (7.4) | 0 | 7 (25.9) | 3 (11.1) | 1 (3.7) | NA |
| R | 2 (7.4) | 5 (18.5) | 19 (70.4) | 19 (70.4) | 14 (51.9) | 10 (37.0) | 14 (51.9) | 8 (29.6) | 9 (33.3) | 9 (33.3) | 4 (14.8) | 3 (11.1) | 17 (63.0) | 6 (22.2) | 3 (11.1) | 5 (18.5) | 4 (14.8) | NA |
| P. aeruginosa (n=19) | ||||||||||||||||||
| S | 14 (73.7) | 13 (68.4) | 2 (10.5) | 4 (21.1) | 5 (26.3) | 9 (47.4) | 6 (31.6) | 16 (84.2) | 11 (57.9) | 10 (52.6) | 15 (78.9) | 8 (42.1) | 7 (36.8) | 13 (68.4) | 9 (47.4) | 12 (63.2) | 17 (89.5) | NA |
| I | 0 | 0 | 0 | 0 | 5 (26.3) | 2 (10.5) | 3 (15.8) | 1 (5.3) | 0 | 1 (5.3) | 0 | 1 (5.3) | 3 (15.8) | 0 | 7 (36.8) | 3 (15.8) | 0 | NA |
| R | 5 (26.3) | 6 (31.6) | 17 (89.5) | 17 (89.5) | 9 (47.4) | 8 (42.1) | 10 (52.6) | 2 (10.5) | 8 (42.1) | 8 (42.1) | 4 (21.1) | 10 (52.6) | 9 (47.4) | 6 (31.6) | 3 (15.8) | 4 (21.1) | 2 (10.5) | NA |
| S. aureus (n=9) | ||||||||||||||||||
| S | NA | NA | 5 (55.6) | 7 (77.8) | 8 (88.9) | 5 (55.6) | 8 (88.9) | 7 (77.8) | 6 (66.7) | 6 (66.7) | 7 (77.8) | 8 (88.9) | 1 (11.1) | 7 (77.8) | 7 (77.8) | 5 (55.6) | 5 (55.6) | 9 (100) |
| I | NA | NA | 1 (11.1) | 0 | 0 | 1 (11.1) | 0 | 0 | 1 (11.1) | 2 (22.2) | 0 | 0 | 3 (33.3) | 1 (11.1) | 2 (22.2) | 3 (33.3) | 3 (33.3) | 0 |
| R | NA | NA | 3 (33.3) | 2 (22.2) | 1 (11.1) | 3 (33.3) | 1 (11.1) | 2 (22.2) | 2 (22.2) | 1 (11.1) | 2 (22.2) | 1 (11.1) | 5 (55.6) | 1 (11.1) | 0 | 1 (11.1) | 1 (11.1) | 0 |
| S. pneumoniae (n=37) | ||||||||||||||||||
| S | NA | NA | 26 (70.3) | 26 (70.3) | 27 (73.0) | 30 (81.1) | 26 (70.3) | 26 (70.3) | 28 (75.7) | 30 (81.1) | 26 (70.3) | 28 (75.7) | 27 (73.0) | 30 (81.1) | 27 (73.0) | 32 (86.5) | 35 (94.6) | 9 (100) |
| I | NA | NA | 2 (5.3) | 2 (5.3) | 4 (10.8) | 2 (5.4) | 2 (5.3) | 3 (8.1) | 3 (8.1) | 2 (5.4) | 4 (10.8) | 0 | 2 (5.4) | 0 | 4 (10.8) | 2 (5.3) | 2 (5.3) | 0 |
| R | NA | NA | 9 (24.3) | 9 (24.3) | 6 (16.2) | 5 (13.3) | 9 (24.3) | 8 (21.6) | 6 (16.2) | 5 (13.5) | 7 (18.9) | 9 (24.3) | 8 (21.6) | 7 (18.9) | 6 (16.2) | 3 (8.1) | 0 | 0 |
| S. viridans (n=36) | ||||||||||||||||||
| S | NA | NA | 15 (41.7) | 20 (55.6) | 28 (77.8) | 27 (75.0) | 26 (72.2) | 27 (75.0) | 27 (75.0) | 29 (80.6) | 30 (83.3) | 25 (69.4) | 23 (63.9) | 30 (83.3) | 22 (61.1) | 29 (80.6) | 30 (83.3) | 9 (100) |
| I | NA | NA | 8 (22.2) | 8 (22.2) | 4 (11.1) | 4 (11.1) | 8 (22.2) | 6 (16.7) | 5 (13.9) | 4 (11.1) | 4 (11.1) | 1 (2.8) | 7 (19.4) | 0 | 6 (16.7) | 4 (11.1) | 4 (11.1) | 0 |
| R | NA | NA | 13 (36.1) | 8 (22.2) | 4 (11.1) | 5 (13.9) | 2 (5.6) | 3 (8.3) | 4 (11.1) | 3 (8.3) | 2 (5.6) | 10 (27.8) | 6 (16.7) | 6 (16.7) | 8 (22.2) | 3 (8.3) | 2 (5.6) | 0 |
| All organisms (n=181) | ||||||||||||||||||
| S | 80 (84.2)a | 75 (78.9)a | 66 (36.5) | 86 (47.5) | 90 (49.7) | 116 (64.1) | 95 (52.5) | 128 (70.7) | 122 (67.4) | 127 (70.2) | 149 (82.3) | 123 (68.0) | 85 (47.0) | 137 (75.7) | 108 (59.7) | 126 (69.6) | 149 (82.3) | 86 (100)b |
| I | 0a | 1 (1.1)a | 16 (8.8) | 15 (8.3) | 33 (18.2) | 14 (7.7) | 22 (12.2) | 16 (8.8) | 12 (6.6) | 11 (6.1) | 9 (5.0) | 8 (4.4) | 28 (15.5) | 2 (1.1) | 47 (26.0) | 27 (14.9) | 15 (8.3) | 0b |
| R | 15 (15.8)a | 19 (20.0)a | 99 (54.7) | 80 (44.2) | 58 (32.0) | 51 (28.2) | 64 (35.4) | 37 (20.4) | 47 (26.0) | 43 (23.8) | 23 (12.7) | 50 (27.6) | 68 (37.6) | 42 (23.2) | 26 (14.4) | 28 (15.5) | 17 (9.4) | 0b |
Notes: aAmong 95 Gram-negative isolates including A. baumannii, E. coli, Enterobacter. spp, K. pneumoniae, and P. aeruginosa. bAmong 86 Gram-positive isolates including S. aureus, S. pneumoniae, S. viridans, and Staphylococcus non-haemolyticus.
Abbreviations: AMC, amoxicillin-clavulanate; AMK, amikacin; CAZ, ceftazidime; CFP, cefoperazone; CFZ, cefazolin; CIP, ciprofloxacin; CRO, ceftriaxone; CTX, cefotaxime; GEN, gentamycin; I, intermediate; IPM, imipenem; LVX, levofloxacin; MEM, meropenem; MXF, moxifloxacin; NA, not applicable; PEN, Penicillin; PIP, piperacillin-tazobactam; R, resistant; S, sensitive; SAM, ampicillin-sulbactam; SXT, trimethoprim-sulfamethoxazole; TIC, ticarcillin-clavulanate; VAN, vancomycin.