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. 2019 Nov 25;12:3663–3675. doi: 10.2147/IDR.S217842

Table 5.

Multivariate Analysis Of Risk Factors For Mortality Among CAP Patients

Variable CAP Mortality Univariate Analysis Multivariate Analysis
No (n=126) Yes (n=55) OR 95% CI p-value aOR 95% CI p-value
Host factors
 Male 82(65.1) 35(63.6) 0.939 0.485–1.817 0.852 0.483 0.190–1.229 0.127
 Age>60 40(31.7) 26(47.3) 1.928 1.008–3.688 0.047 1.482 0.585–3.751 0.407
 Cardiovascular disease 9(7.1) 12(21.8) 3.628 1.428–9.216 0.007 2.401 0.684–8.422 0.171
 Neoplasm 21(16.7) 25(45.5) 4.167 2.053–8.458 <0.001 2.755* 1.031–7.361 0.043
 Diabetes mellitus 24(19.0) 27(49.1) 4.098 2.054–8.177 <0.001 2.098 0.780–5.642 0.142
 Liver disease 7(5.6) 6(10.9) 2.082 0.666–6.509 0.208 3.800 0.633–22.810 0.144
 Renal insufficiency 18(14.3) 13(23.6) 1.857 0.837–4.123 0.128 1.917 0.592–6.201 0.277
 PSI class ≥3 92(73.0) 53(96.4) 9.793 2.262–42.407 0.002 9.188* 1.510–55.891 0.016
 Day-3 improvement 77(61.1) 4(7.3) 0.050 0.017–0.147 <0.001 0.055* 0.016–0.190 <0.001
Agent factor
 MDR-bacterial infections 19(15.1) 25(45.5) 4.693 2.282–9.651 <0.001 1.259 0.471–3.361 0.646
Treatment factor
 Antibiotic combination 14(11.1) 16(29.1) 3.282 1.468–7.338 0.004 2.424 0.717–8.196 0.154

Note: *Statistically significant in multivariate analysis, the aOR CI95% does not include a value of 1.

Abbreviations: CAP, community-acquired pneumonia; MDR, multidrug resistance; OR, odds ratio; aOR, adjusted odds ratio; PSI, pneumonia severity index.