Table 5.
Variable | CAP Mortality | Univariate Analysis | Multivariate Analysis | |||||
---|---|---|---|---|---|---|---|---|
No (n=126) | Yes (n=55) | OR | 95% CI | p-value | aOR | 95% CI | p-value | |
Host factors | ||||||||
Male | 82(65.1) | 35(63.6) | 0.939 | 0.485–1.817 | 0.852 | 0.483 | 0.190–1.229 | 0.127 |
Age>60 | 40(31.7) | 26(47.3) | 1.928 | 1.008–3.688 | 0.047 | 1.482 | 0.585–3.751 | 0.407 |
Cardiovascular disease | 9(7.1) | 12(21.8) | 3.628 | 1.428–9.216 | 0.007 | 2.401 | 0.684–8.422 | 0.171 |
Neoplasm | 21(16.7) | 25(45.5) | 4.167 | 2.053–8.458 | <0.001 | 2.755* | 1.031–7.361 | 0.043 |
Diabetes mellitus | 24(19.0) | 27(49.1) | 4.098 | 2.054–8.177 | <0.001 | 2.098 | 0.780–5.642 | 0.142 |
Liver disease | 7(5.6) | 6(10.9) | 2.082 | 0.666–6.509 | 0.208 | 3.800 | 0.633–22.810 | 0.144 |
Renal insufficiency | 18(14.3) | 13(23.6) | 1.857 | 0.837–4.123 | 0.128 | 1.917 | 0.592–6.201 | 0.277 |
PSI class ≥3 | 92(73.0) | 53(96.4) | 9.793 | 2.262–42.407 | 0.002 | 9.188* | 1.510–55.891 | 0.016 |
Day-3 improvement | 77(61.1) | 4(7.3) | 0.050 | 0.017–0.147 | <0.001 | 0.055* | 0.016–0.190 | <0.001 |
Agent factor | ||||||||
MDR-bacterial infections | 19(15.1) | 25(45.5) | 4.693 | 2.282–9.651 | <0.001 | 1.259 | 0.471–3.361 | 0.646 |
Treatment factor | ||||||||
Antibiotic combination | 14(11.1) | 16(29.1) | 3.282 | 1.468–7.338 | 0.004 | 2.424 | 0.717–8.196 | 0.154 |
Note: *Statistically significant in multivariate analysis, the aOR CI95% does not include a value of 1.
Abbreviations: CAP, community-acquired pneumonia; MDR, multidrug resistance; OR, odds ratio; aOR, adjusted odds ratio; PSI, pneumonia severity index.