Table 5.

Multivariate analysis result of factors associated with overall survival post-RAE.

	Variable included to MVA	p-value	HR	95%CI
1	Tumor differentiation level (good/moderate vs. poor)	<0.0001	5.3	2.6–10.7
2	Sum of largest diameters of two liver target lesions	<0.0001	1.15	1.09–1.21
3	Number of EHD sites (range, 0–4)	0.016	1.41	1.07–1.87
4	CEA level at time of RAE (ng/ml)	<0.001	1.00009	1.00006–1.0001
5	Albumin	0.005	0.46	0.27–0.79
6	ALT (alanine aminotransferase)	<0.0001	1.02	1.01–1.03
7	Lymphovascular invasion on pathology of primary (yes/no)	>0.05	Excluded by stepwise forward selection
8	Pre-RAE NLR (neutrophil/lymphocyte ratio)	>0.05	Excluded by stepwise forward selection

EHD-extrahepatic disease; CEA-carcinoembryonic antigen level, RAE-radioembolization.