Table 2:

Stratification of mice into five treatment groups and evaluation of responses to therapy, toxicity, and recurrence. CR: complete response meaning no evidence of the tumor mass. PR: partial response meaning a decrease in tumor volume (≥25%). NR: no response meaning no significant decrease in tumor mass. Recurrence: increase in tumor mass after a complete or partial response. * Drug-related observable toxicity during treatment: More than 10% weight loss in a week or more than 20% weight loss over any time period; diarrhea, bulky ascites, distended abdomen, or lethargy.

Group	Treatment	Mice/group	CR	PR	NR	Treatment-Related Toxicity*	Recurrence
G1	Vehicle control	5	0	0	5	0	N/A
G2	Cisplatin+ Paclitaxel 5 + 15 (mg/kg)	5	0	0	5	0	N/A
G3	Irinotecan 40 (mg/kg)	5	1	3	1	0	3
G4	Irinotecan 80 (mg/kg)	5	3	2	0	3	2
G5	ASC-shCE2:nLuc + Irinotecan 40 (mg/kg)	5	4	1	0	0	1