Figure 1. Some broadly neutralizing antibodies (bnAbs) are less efficient in blocking cell to cell virus transfer.

Representative examples of neutralization against cell-free (hollow squares), mature dendritic cell (DC) associated (filled squares) and infected CD4+ T cells (diamonds). Neutralization is against primary HIV-1 variant, Q23. The x-axis shows the amount of input VRC01 (A) and PGT121 (B) in log µg/ml, and the y-axis shows the percent inhibition relative to infection without any antibody. Each point represents an average of at least three independent experiments performed in triplicate and is the mean percent inhibition with standard errors of mean.