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. 2019 Nov 1;8:e50033. doi: 10.7554/eLife.50033

Figure 7. Model for intestinal infection-regulated microbial perception.

Figure 7.

Rapid chemosensation of P. aeruginosa resulting in the induction of daf-7 expression in the ASJ neuron pair is insufficient for eliciting avoidance behavior. Intestinal infection leading to bloating activates NPR-1/GPCR and DAF-7/TGF-β neuroendocrine pathways, driving the evacuation of low O2 P. aeruginosa lawns and change in preference from relatively lower O2 lawns of P. aeruginosa to relatively higher O2 lawns of E. coli.