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. 2019 Oct 7;25(11):717–728. doi: 10.1093/molehr/gaz049

Figure 1.

Figure 1

Effect of F0 diet on mitochondrial mass and membrane potential and Oma1 protein expression in offspring oocytes. (A and E) Representative images of oocytes derived from chow and HF/HS groups. Quantification of mitochondrial mass (MTDR), mitochondrial membrane potential (MTRC/MTDR) and lipid droplets (BODIPY 409/503) in oocytes derived from F1 (B), F2 (C) and F3 (D) generations (n = 29–30 oocytes derived from five mice/diet/generation). Quantification of Oma1 protein expression in F1 (F), F2 (G) and F3 (H) oocytes (n = 28–30 oocytes derived from five mice/diet/generation). Scale bar = 10 μm. Data are represented as mean ± SEM. **P < 0.01, ***P < 0.001, ****P < 0.0001.