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Gains in percentage of scheduled workplace productivity per week at Months 3 and 6 of treatment. Mean gains in the percentage of scheduled workplace hours worked, defined as − 1 × LS mean change from baseline in percentage of scheduled workplace hours lost due to absenteeism, presenteeism, and total (absenteeism + presenteeism). ***p < 0.001; **p < 0.01; *p < 0.05. BID twice daily, CI confidence interval, LS least squares, PBO placebo, QD once daily
