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. 2019 Nov 29;9:17936. doi: 10.1038/s41598-019-54283-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Intracranially implanted NanoMesh significantly prolong survival in 9L intracranial gliosarcoma: (a) Trial 1, Day 0 implant, Implanted UC-1 and UC-2 NanoMeshes resulted in 86% and 100% LTS, respectively; (b) Trial 2, Day 5 implant, a significant increase in median survival of 36 and 37 days for UC-1 and UC-2 treated groups, respectively, (p < 0.0001 vs. control) was observed; (c) Trial 3, Day 5 implant, confirmed significant increase in median survival in UC-1 treated animals with 50% LTS (p < 0.0001 vs. control).