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. 2019 Nov 29;9:17980. doi: 10.1038/s41598-019-52971-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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IDET suppresses the proliferation of multiple breast cancer cells in a dose- and time- dependent manner. Breast cancer cell lines (T47D, MCF-7, MDA-MB-468, MDA-MB-453) were exposed to (A) different concentrations of IDET for 72 hrs or (B) 25 µM IDET for 24–72 hrs. The proliferation of cells was assessed by measuring the mitochondrial reductase activity. The values indicate mean ± SE (3 experiments). *Shows the significance level in comparison to untreated group; P < 0.05. IDET, isodeoxyelephantopin.