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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Connect Tissue Res. 2019 Aug 23;61(1):82–94. doi: 10.1080/03008207.2019.1641495

Figure 2: Intra-articular levels of CTXII, IL1β, IL6, TNFα, and IFNγ in the Rat MCLT+MMT Model of Knee OA.

Figure 2:

Magnetic capture revealed elevated levels of CTXII and IL6 in the MCLT+MMT operated joint relative to contralateral and skin-incision controls (Row 1 and Row 3). Differences in IL1β, TNFα, and IFNγ were not observed. Age was found to affect the measured levels of CTXII in the synovial fluid, aligning with prior results describing decreases in serum-level CTXII with age36; 37. Relevant ANOVA main effect and interaction p-values are provided next to each figure; p-values are associated with a post-hoc Tukey’s HSD test. Data linked by a line are from the same animal (paired scatterplot).