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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Connect Tissue Res. 2019 Aug 23;61(1):82–94. doi: 10.1080/03008207.2019.1641495

Figure 3: Serum levels of CTXII, IL1β, IL6, TNFα, and IFNγ in the Rat MCLT+MMT Model of Knee OA.

Figure 3:

Serum was collected at the time of euthanasia, and then assessed using a CTXII and cytokine multiplex assay. Differences were not observed between MCLT+MMT and skin incision animals at 8 weeks after surgery. Age was found to affect the measured levels of CTXII in the serum, again aligning with prior results on CTXII concentration related to age36; 37. Relevant ANOVA main effect and interaction p-values are provided in the statistical table next to each figure. Note, IFNγ concentrations were only above the assay detection threshold in 1 of the 48 animals assessed; as such, these data are not shown.