Figure 1.

Impact of control scrambled (SCR) and targeted Gαi₂ intracerebroventricular oligodeoxynucleotide (ODN) infusion [25 µg (5 µl)⁻¹ day⁻¹ for 7 days] and minocycline (MINO)–ODN co‐infusion [ODN, 25 µg (5 µl)⁻¹ day⁻¹; MINO: 120 µg day⁻¹ for 7 days in high‐salt (HS) group only] in male Sprague–Dawley rats receiving 7 days of normal‐salt (NS; 0.6% NaCl) or HS (4% NaCl) diets on: (a,b) mean arterial pressure (MAP) as assessed via radiotelemetry over 5 days preceding the experimental diet and the 7 days of the experimental diet; (c) plasma noradrenaline (NA) concentrations; (d) urinary angiotensinogen (UAGT) concentrations; and (e) plasma renin activity. (n = 6 per group, ^* P < 0.05 versus pre‐experimental diet NS in respective ODN treatment group; ^τ P < 0.05 versus 7 days of experimental HS in respective ODN treatment group; ^ϕ P < 0.05 versus 7 days of experimental NS diet in the respective ODN treatment group, means ± SD.)