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. 2019 Nov 29;7:334. doi: 10.1186/s40425-019-0810-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Kaplan Meier analysis of recurrence-free survival (RFS) and overall survival (OS) by levels of soluble immune checkpoint proteins in ccRCC patients. a Survival curve of RFS according to the level of sPDL2. b-c Survival curves of OS according to the levels of sBTLA, sTIM3, respectively. High- and low-level groups were dichotomized by the logistic regression spline model