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. 2019 Nov 29;10:362. doi: 10.1186/s13287-019-1490-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — fMSCs restored POI disease by targeting MT1. a Western blot analysis of MT1 in hGCs-MT1^KD cells. b Western blot analysis of JNK1, PCNA, and AMPK expression levels in different treatment groups. c Western blot assessment of MT1 after administration of the MT1 antagonist luzindole at different concentrations (10 μM, 20 μM, 40 μM, and 80 μM) in normal hGCs. d Western blot assessment of JNK1, PCNA, and AMPK in different treatment groups (luzindole, 40 μM). e KI67 expression levels were evaluated in different treatment groups by FACS. Data are represented as the mean ± SD. ***p < 0.05 (compared with the MT1^KD group)