Table 3.
Number of samples (and percentages) found to be positive for the three different peptide serology markers
| Sample set | Number (%) of plasma samples above “spot intensity cut-off” for peptide | |||
|---|---|---|---|---|
| OvMP-1 | OvMP-23 | OvNMP-48 | 3-peptide positives | |
| Known onchocerciasis status | ||||
| Nodule positive (Ghana, n = 77) | 76 (98.7) | 75 (97.4) | 74 (96.1) | 72 (93.5) |
| B. malayi (Indonesia, n = 19) | 18 (94.7) | 8 (42.1) | 3 (15.8) | 1 (5.3) |
| W. bancrofti (Sri Lanka, n = 8; Tahiti, n = 2) | 2 (20.0) | 2 (20.0) | 2 (20.0) | 1 (10.0) |
| Healthy controls (Belgium, n = 84) | 0 (0) | 4 (4.8) | 4 (4.8) | 0 (0) |
| South America (n=89) | 1 (1.1) | 10 (11.2) | 7 (7.9) | 0 (0) |
| Unknown onchocerciasis status | ||||
| Kenya, Kisumu (n = 98) | 86 (87.8) | 55 (56.1) | 45 (45.9) | 30 (30.6) |
| Kenya, Siaya (n = 98) | 83 (84.7) | 66 (67.3) | 69 (70.4) | 57 (58.2) |
| STH/S. mansoni (Ethiopia, n = 24) | 3 (12.5) | 5 (20.8) | 2 (8.3) | 0 (0) |
| Endemic controls (Ghana, n = 48) | 46 (95.8) | 46 (95.8) | 43 (89.6) | 40 (83.3) |