Table 5.
Different PPVs according to pregnancies characteristics
| Clinical features | PPV of T21 (%) | PPV of T18 (%) | PPV of T13 (%) | PPV of SCAs (%) | PPV of other chromosome aneuploidy (%) | PPV of CNVs (%) |
|---|---|---|---|---|---|---|
| Fetal structural abnormalities by B-ultrasound | 0 | 100 | 0 | 0 | 0 | 100.00 |
| Increased NT | 100 | 100 | / | 50.00 | 0 | 37.50 |
| Othera | / | / | / | / | / | 0.00 |
| High risk of serological screening | 86.67 | 100 | 100 | 28.57 | 12.50 | 11.11 |
| Critical risk of serological screening | 71.74 | 33.33 | 9.09 | 28.57 | 0 | 50.00 |
| Advanced maternal age (≥ 35 years) | 89.29 | 60.00 | 9.09 | 30.77 | 15.38 | 5.26 |
| No clinical indications | 33.33 | 0 | 25.00 | 35.71 | 0 | 41.67 |
| Total | 79.23 | 54.84 | 13.79 | 33.04 | 9.09 | 28.99 |
“/” indicates no data
aPatients with interventional surgery contraindications: reoperative infection, placenta previa, placental bleeding, poor pregnancy history.