Table 1.

Endemic infections that may enhance HIV susceptibility in Sub-Saharan Africa

Infection	Main causative agent (s) in SSA	Primary tissue site(s) involved
Malaria	Plasmodium spp.- mainly P. falciparum	Blood, liver
Soil transmitted helminthiases	Ascaris, Trichuris, hookworms (e.g. Necator americanus)	Gut lumen
Lymphatic filariasis	Wuchereria bancrofti	Lymphatic system, blood
Schistosomiasis	Schistosoma spp.
Intestinal schistosomiasis	S. mansoni	Blood vessels surrounding gut, gut mucosa
Genitourinary schistosomiasis	S. haematobium	Blood vessels surrounding genitourinary tract, genitourinary mucosa