Table 1.
clinicopathological characteristics of adrenocortical carcinomas in WCH cohort
| Characteristics | Number (%) | FSCN1 | FOXM1 | ||||
|---|---|---|---|---|---|---|---|
| High | Low | p | High | Low | p | ||
| Gender | |||||||
| Female | 33 (64.71) | 23 | 8 | 0.06 | 17 | 16 | 0.57 |
| Male | 18 (35.29) | 8 | 10 | 11 | 7 | ||
| Age | |||||||
| < 65 | 44 (86.27) | 30 | 14 | 0.23 | 25 | 19 | 0.69 |
| ≥ 65 | 7 (13.73) | 3 | 4 | 3 | 4 | ||
| Hormone secretion | |||||||
| No | 28 (54.90) | 17 | 11 | 0.57 | 9 | 19 | 0.001* |
| Yes | 23 (45.10) | 16 | 7 | 19 | 4 | ||
| Laterality | |||||||
| Left | 29 (56.86) | 16 | 13 | 0.14 | 19 | 10 | 0.10 |
| Right | 22 (43.14) | 17 | 5 | 9 | 13 | ||
| Tumor size (cm) | |||||||
| < 7.5 | 27 (52.94) | 20 | 7 | 0.16 | 15 | 12 | 1 |
| ≥ 7.5 | 24 (47.06) | 13 | 11 | 13 | 11 | ||
| ENSAT tumor stage | |||||||
| 1 | 4 (7.84) | 10 | 11 | 0.04* | 10 | 11 | 0.41 |
| 2 | 17 (33.33) | ||||||
| 3 | 20 (39.22) | 23 | 7 | 18 | 12 | ||
| 4 | 10 (19.61) | ||||||
| Ki67 index | |||||||
| < 20% | 30 (58.82) | 16 | 14 | 0.07 | 15 | 15 | 0.57 |
| ≥ 20% | 21 (41.17) | 17 | 4 | 13 | 8 | ||
| Symptoms at diagnosis | |||||||
| No | 15 (29.41) | 7 | 8 | 0.11 | 6 | 9 | 0.22 |
| Yes | 36 (70.59) | 26 | 10 | 22 | 14 | ||