Table 2.
Isolated uropathogens and antimicrobial resistance profiles
| Uropathogensa | All patients (n = 552) | Older (n = 329) | Non-Older (n = 223) | P value |
|---|---|---|---|---|
| Escherichia coli | 393 (71.2) | 206 (62.6) | 187(83.9) | < 0.001 |
| Amoxicillin | 254 (69.2) | 137 (71.4) | 117 (67) | 0.35 |
| Amoxicillin-clavulanate | 52 (13.3) | 33 (16.2) | 19 (10.2) | 0.080 |
| Cefuroxime sodium | 38 (9.7) | 26 (12.6) | 12 (6.4) | 0.038 |
| Ceftriaxoneb | 35 (8.9) | 23 (11.2) | 12 (6.4) | 0.099 |
| Gentamicin | 30 (7.7) | 21 (10.2) | 9 (4.8) | 0.043 |
| Fluoroquinolones | 153 (38.9) | 100 (48.5) | 53 (28.3) | < 0.001 |
| Co-trimoxazol | 102 (26.8) | 56 (28.3) | 46 (25.3) | 0.51 |
| Fosfomycine | 8 (2.1) | 6 (3.1) | 2 (1.1) | 0.28 |
| Klebsiella spp.c | 56 (10.1) | 40 (12.2) | 16 (7.2) | 0.057 |
| Amoxicilline-clavulanate | 13 (23.2) | 8 (20) | 5 (31.3) | 0.48 |
| Ceftriaxoned | 12 (21.4) | 9 (22.5) | 3 (18.8) | 1 |
| Fluoroquinolones | 15 (26.8) | 12 (30) | 3 (18.8) | 0.51 |
| Co-trimoxazol | 11 (20.8) | 8 (21.1) | 3 (20) | 1 |
| ESBL and AmpC producing E. coli and Klebsiella spp. | 48 (10.7) | 33 (13.4) | 15 (7.4) | 0.041 |
| Enterobacter spp.e | 21 (3.8) | 19 (5.8) | 2 (0.9) | 0.003 |
| Serratia spp. | 4 (0.7) | 3 (0.9) | 1 (0.4) | 0.65 |
| Citrobacter spp. | 4 (0.7) | 1 (0.3) | 3 (1.3) | 0.3 |
| Morganella spp. | 5 (0.9) | 4 (1.2) | 1 (0.4) | 0.65 |
| Proteus mirabilis | 17 (3.1) | 14 (4.3) | 3 (1.3) | 0.052 |
| Pseudomona aeruginosa | 25 (4.5) | 20 (6.1) | 5 (2.2) | 0.033 |
| Fluoroquinolones | 7 (28) | 7 (35) | 0 | 0.27 |
| Other Gram negative bacteriaf | 2 (0.4) | 2 (0.6) | 0 | 0.51 |
| Gram positive bacteria | 22 (4) | 17 (5.2) | 5 (2.2) | 0.085 |
| Enterococcus spp.g | 16 (2.9) | 12 (3.6) | 4 (1.8) | 0.20 |
| Staphylococcus spp. h | 6 (1.1) | 5 (1.5) | 1 (0.4) | 0.41 |
| Candida spp.i | 3 (0.5) | 3 (0.9) | 0 | 0.27 |
Abbreviations: ESBL extended-spectrum beta-lactamase
aData presented as number of patients (percentages). bInclude 32 (91.4%) ESBL and 3 (8.6%) AmpC producing strains. cInclude 47 (84%) K. pneumoniae and 9 (16%) K. oxytoca strains. dInclude 9 (75%) ESBL and 3 (25%) AmpC producing strains. eInclude 18 (85.7%) E. cloacae and 3 (14.3%) de E. aerogenes strains. fInclude one P. stuartii strain and one A. baumannii strain. gInclude 11 (68.7%) E. faecalis, 4 (25%) Enterococcus spp. and 1 (6.3%) E. faecium strains. hInclude 6 (83.3%) S. aureus and 1 (16.7%) S. capitis strain. iInclude 2 C. albicans and 1 C. tropicalis strains