Table 3.
Univariate and multivariate analysis of risk factors associated with febrile urinary tract infection caused by multidrug-resistant organisms
| Characteristicsa | MDRO infection (n = 135) | Non-MDRO infection (n = 414) | P value2 | OR (95% CI) | P value3 |
|---|---|---|---|---|---|
| Older males | 98 (72.6) | 228 (55.1) | < 0.001 | ||
| Previous hospital admission | 46 (34.1) | 81 (19.6) | 0.001 | ||
| Long term care facility | 23 (17) | 22 (5.3) | < 0.001 | 2.4 (1.06–5.9) | 0.037 |
| IV home-day hospital treatment | 1 (0.7) | 12 (2.9) | 0.2 | ||
| Specialized nursing care | 2 (1.5) | 5 (1.2) | 0.68 | ||
| Indwelling urethral catheter | 29 (21.5) | 46 (11.1) | 0.002 | ||
| Long-term IUC | 21 (15.6) | 19 (4.6) | < 0.001 | ||
| Short-term IUC | 8 (5.9) | 27 (6.5) | 0.8 | ||
| Invasive urinary Instrumentation | 38 (28.1) | 69 (16.7) | 0.003 | ||
| Dementia | 27 (20) | 36 (8.7) | < 0.001 | ||
| Diabetes mellitus | 40 (29.6) | 106 (25.6) | 0.36 | ||
| Chronic kidney failure | 16 (11.9) | 37 (8.9) | 0.32 | ||
| Cirrhosis | 2 (1.5) | 7 (1.7) | 1 | ||
| Neoplasia | 22 (16.3) | 57 (13.8) | 0.46 | ||
| Heart failure | 4 (3) | 4 (1) | 0.1 | ||
| Chronic obstructive lung disease | 30 (22.2) | 70 (16.9) | 0.16 | ||
| Immunosuppressive or corticosteroid treatment | 1 (0.7) | 10 (2.4) | 0.31 | ||
| Previous UTI | 74 (62.2) | 148 (40.1) | < 0.001 | ||
| Urinary tract abnormality | 100 (74.6) | 236 (57) | < 0.001 | 2.2 (1.2–3.8) | 0.006 |
| Previous antibiotic treatment | 71 (53) | 107 (26) | < 0.001 | 3.2 (1.9–5.4) | < 0.001 |
Abbreviations: CI Confidence interval, IUC Indwelling urinary catheter, MDRO Multidrug-resistant organisms, OR Odds ratio, UTI Urinary tract infections
aData presented as numbers of patients (percentages).2Univariate analysis.3Multivariate analysis