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. 2019 Nov 29;19:1160. doi: 10.1186/s12885-019-6381-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — SDC-1 inhibited the phosphorylation of JAK1/STAT3 pathway. pcDNA3.1 or pc-SDC-1 was transfected into SW620 and SW480 cell lines. a-b Western blot analysis was utilized to evaluate the protein levels of p-JAK1, t-JAK1, p-STAT3 and t-STAT3. β-actin was used as an internal reference for normalizing the protein expression. ***p < 0.001