Table 2.
Functional Enrichment Analysis of Up-Regulated Genes Were Significantly Enriched in Biological Process Terms (24h)
| Category | ID | Term/gene function | GeneID | Gene count | pvalue |
|---|---|---|---|---|---|
| GO_TERM_BP | GO:0001503 | Ossification | TOB1/FSTL3/ANO6/FGFR3/ID1/ID3/JUND/SMAD3/TP53INP2/BMPR1A/BMPR2/KLF10/TMSB4X/TUFT1/KAZALD1/CAT/IFITM1/DHRS3/EIF2AK3/ISG15 | 20 | 1.28E-07 |
| GO_TERM_BP | GO:0007179 | Transforming growth factor beta receptor signaling pathway | CDKN2B/ID1/SMAD3/SMAD7/SMAD9/PTPRK/SKIL/BMPR1A/KLF10/CAV1/CAV2/ADAM9 | 12 | 3.58E-06 |
| GO_TERM_BP | GO:0007178 | Transmembane receptor protein serine/threonine kinase signaling pathway | TOB1/FSTL3/CDKN2B/HES1/ID1/SMAD3/SMAD7/SMAD9/SKIL/BMPR1A/BMPR2/KLF10/CAV1/CAV2/ADAM9 | 16 | 6.40E-06 |
| GO_TERM_BP | GO:0030282 | Bone Mineralization | ANO6/FGFR3/SMAD3/BMPR1A/BMPR2/KLF10/TUFT1/EIF2AK3/ISG15 | 9 | 6.56E-06 |
| GO_TERM_BP | GO:0071560 | Cellular response to transforming growth factor beta stimulus | CDKN2B/ANKRD1/ID1/SMAD3/SMAD7/SMAD9/PTPRK/SKIL/BMPR1A/KLF10/CAV1/CAV2/ADAM9 | 13 | 8.08E-06 |
| GO_TERM_BP | GO:0071559 | Response to transforming growth factor beta | CDKN2B/ANKRD1/ID1/SMAD3/SMAD7/SMAD9/PTPRK/SKIL/BMPR1A/KLF10/CAV1/CAV2/ADAM9 | 13 | 9.80E-06 |
| GO_TERM_BP | GO:0050678 | Regulating of epithelial cell proliferation | CDKN1B/CDKN2B/ANG/HOXA5/HES1/ID1/MIR24-2/SMAD3/PTPRK/PEX2/BMPR1A/BMPR2/CAV1/CAV2/MAGED1 | 15 | 1.53E-05 |
| GO_TERM_BP | GO:0060337 | Type I interferon signaling pathway | IRF9/IFI6/IFI27/IFIT2/IFIT1/IP6K2/IFITM1/ISG15 | 8 | 2.15E-05 |
| GO_TERM_BP | GO:0071357 | Cellular response to type I interferon | IRF9/IFI6/IFI27/IFIT2/IFIT1/IP6K2/IFITM1/ISG15 | 8 | 2.15E-05 |
| GO_TERM_BP | GO:0050673 | Epithelial cell proliferation | CDKN1B/CDKN2B/ANG/HOXA5/HES1/ID1/ID2/MIR24-2/SMAD3/PTPRK/PEX2/BMPR1A/BMPR2/CAV1/CAV2/MAGED1 | 16 | 2.63E-05 |
| GO_TERM_BP | GO:0034340 | Repose to type I interferon | IRF9/IFI6/IFI27/IFIT2/IFIT1/IP6K2/IFITM1/ISG15 | 8 | 3.22E-05 |
| GO_TERM_BP | GO:0030278 | Regulation of ossification | TBO1/ANO6/ID1/ID3/JUND/SMAD3/BMPR1A/BMPR2/IFITM1/DHRS3/ISG15 | 11 | 3.49E-05 |