Table 3.
Size of the ten protein peaks with the highest mean relative intensities from MALDI–TOF analysis of glioblastoma cyst fluid samples (n = 24)
| Dalton | Relative intensity | % Positive samples | Difference to CSF (p value) | Potential underlying proteins (Expasy TagIdenta) |
|---|---|---|---|---|
| 6433 | 0.36 | 75.0 | 0.0004 | ApoC1, LuzP6, Sim27, Stp1 |
| 1865 | 0.23 | 29.2 | 0.0094 | No human proteins: HIV-1 Gag polyprotein spacer peptide 2 |
| 4967 | 0.20 | 54.2 | ns | Ca2d4, Cstf3, Hmhb1, Tjap1 |
| 7565 | 0.18 | 33.3 | ns | Ccl18, Hcst, Rad1, Sg1d1 |
| 6632 | 0.17 | 62.5 | 0.0189 | ApoC1, cholecystokinin, Cxl17, RS30 |
| 2661 | 0.16 | 29.2 | 0.0479 | Humanin-like 5, humanin-like 8 |
| 8564 | 0.12 | 66.7 | ns | ApoA2, Hsbp1, interleukin-8, ubiquitin |
| 3436 | 0.09 | 25.0 | ns | Histatin-1, insulin B-chain |
| 3851 | 0.09 | 25.0 | ns | Tumor necrosis factor intracellular domain 2, insulin-like 3B chain |
| 1778 | 0.09 | 20.8 | 0.0496 | No human proteins: HIV-2 Gag polyprotein spacer peptide 1, mammalian neurogranins |
p value obtained by two-sided Fisher’s exact test using a 2 × 2 contingency table
ns not significant
aExpasy TagIdent accessed October 13, 2018: Mw as given, Mw range 0.3%, organism 9606 or none