| Trial name or title | SPRING: an RCT study of probiotics in the prevention of gestational diabetes mellitus in overweight and obese women. |
| Methods | DESIGN: randomised controlled trial. BLINDING: double blind for probiotics/placebo. DURATION: supplementation with probiotic/placebo from early pregnancy until delivery. LOCATION: Australia. |
| Participants | Overweight and obese women, < 16 weeks' gestation at study entry, 18‐45 years. |
| Interventions | PROBIOTIC: Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12, Chr. Hansen, Hoersholm, Denmark, 109 colony‐forming units/d each). PLACEBO: microcrystalline cellulose and dextrose anhydrate. |
| Outcomes | Glucose tolerance by OGTT using IADPSG guidelines between 24‐28 weeks' gestation. |
| Starting date | November 2012. |
| Contact information | A/Prof Leonie Callaway, The University of Queensland. |
| Notes | ACTRN12611001208998 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.