Liu 2003.
Methods | Design: RCT Randomization method: not reported Method of allocation concealment: not reported Blinding method: not reported Stratification: not used |
Participants | Inclusion: neonates with HIE Exclusion: Nil Number of patients randomized (Treatment: Control): 36: 36 Dropouts (Treatment: Control): 2: 6 Age (Treatment: Control): not reported Number of boys (Treatment: Control): 20: 17 Stage of HIE: Treatment group: moderate (26), severe (10); Control group: moderate (23), severe (9) |
Interventions | Treatment group: acupuncture + acupressure + conventional supportive care and rehabilitation Acupuncture started at 6 months to 2 years old. Treatment was applied 10‐15 times per month. Use of needles, selection of acupoints and stimulation method were not reported Acupressure to 10 acupoints: Bai‐hui (GV20), Sishencong (EX‐HN1), Yintang (EX‐HN3), Yamen (GV15), Dazhu (BL11), Zusanli (ST36), Yanlingquan (GB34), Xuanzhong (GB39), Quchi (LI11), and Tongli (HT5) Selection of acupoints might be modified according to syndrome differentiation by Traditional Chinese Medicine. Further details were not provided. Treatment was applied daily for 10 days then rest for 7‐10 days (1 course). Total number of courses was not reported Control: conventional supportive care and rehabilitation alone as in treatment group Duration of treatment: not reported |
Outcomes | Bayley Scales of infant development at 2 years old Frequency of motor developmental delay at 2 years old Frequency of mental retardation at 2 years old Frequency of epilepsy at 2 years old |
Notes | Await clarification of whether needle acupuncture was used |