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. 2013 Jan 31;2013(1):CD007968. doi: 10.1002/14651858.CD007968.pub2

Liu 2003.

Methods Design: RCT
Randomization method: not reported
Method of allocation concealment: not reported
Blinding method: not reported
Stratification: not used
Participants Inclusion: neonates with HIE
Exclusion: Nil
Number of patients randomized (Treatment: Control): 36: 36
Dropouts (Treatment: Control): 2: 6
Age (Treatment: Control): not reported
Number of boys (Treatment: Control): 20: 17
Stage of HIE: Treatment group: moderate (26), severe (10); Control group: moderate (23), severe (9)
Interventions Treatment group: acupuncture + acupressure + conventional supportive care and rehabilitation
Acupuncture started at 6 months to 2 years old. Treatment was applied 10‐15 times per month. Use of needles, selection of acupoints and stimulation method were not reported
Acupressure to 10 acupoints: Bai‐hui (GV20), Sishencong (EX‐HN1), Yintang (EX‐HN3), Yamen (GV15), Dazhu (BL11), Zusanli (ST36), Yanlingquan (GB34), Xuanzhong (GB39), Quchi (LI11), and Tongli (HT5) Selection of acupoints might be modified according to syndrome differentiation by Traditional Chinese Medicine. Further details were not provided. Treatment was applied daily for 10 days then rest for 7‐10 days (1 course). Total number of courses was not reported
Control: conventional supportive care and rehabilitation alone as in treatment group 
 Duration of treatment: not reported
Outcomes Bayley Scales of infant development at 2 years old
Frequency of motor developmental delay at 2 years old
Frequency of mental retardation at 2 years old
Frequency of epilepsy at 2 years old
Notes Await clarification of whether needle acupuncture was used