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. 2015 Mar 5;2015(3):CD009924. doi: 10.1002/14651858.CD009924.pub2

Summary of findings 2. Low‐ and middle‐income countries: Feeding compared to control. CBAs for improving the physical and psychosocial health of disadvantaged children aged three months to five years.

Low‐ and middle‐income countries: Feeding compared to control. CBAs for improving the physical and psychosocial health of disadvantaged children aged three months to five years
Participant or population: Children aged 3 months to 5 years
 Settings: Low‐ and middle‐income countries
 Intervention: Feeding
 Comparison: Control ‐ CBAs
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) Number of participants in meta‐analyses
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
Control ‐ CBA Low‐ and middle‐income countries: Feeding
Weight gain (kg) 
 Follow‐up: 6 months ‐ 1.8 years; average 1 year Weight change of control group ranged from 0.5 to 3.93 kg The mean weight gain (kg) in the intervention group was 0.24 higher (0.09 to 0.39 higher)   1784
 (7 studies) ⊕⊝⊝⊝
 very low¹  
Height gain (cm) 
 Follow‐up: 6 months ‐ 1.8 years; average 1 year Growth in height of control group ranged from 1.88 to 20.1 cm The mean height gain (cm) in the intervention group was 0.52 higher but non‐significant (0.07 lower to 1.10 higher)   1782
 (7 studies) ⊕⊝⊝⊝
 very low¹  
Weight‐for‐age: z‐scores (WAZ) 
 Follow‐up: 9 ‐ 12 months Change in WAZ in the control group ranged from ‐0.42 to 0.07 The mean change in WAZ in the intervention group was 0.27 higher (0.13 lower to 0.68 higher)   999
 (4 studies) ⊕⊝⊝⊝
 very low¹  
Height‐for‐age: z‐scores (HAZ) 
 Follow‐up: 9 ‐ 12 months Change in HAZ in the control group ranged from ‐0.82 to 0.26 There was little mean change in HAZ in the intervention group compared to the control group0.01 higher (0.10 lower to 0.12 higher)   999
 (4 studies) ⊕⊝⊝⊝
 very low¹  
Weight‐ for‐height: z‐scores (WHZ) 
 Follow‐up: 9 ‐ 12 months Change in WHZ in the control group ranged from ‐0.92 to ‐0.01 The mean change in WHZ in the intervention group was 0.29 higher (0.11 lower to 0.69 higher)   999
 (4 studies) ⊕⊝⊝⊝
 very low¹  
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval
GRADE Working Group grades of evidence
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

1Studies are rated at high risk of bias due to lack of randomisation