Comparison 2.

Analysis according to trial design

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Post‐ERCP pancreatitis	12	3450	Risk Ratio (M‐H, Random, 95% CI)	0.51 [0.32, 0.82]
1.1 'Non‐crossover' studies	5	1330	Risk Ratio (M‐H, Random, 95% CI)	0.22 [0.12, 0.42]
1.2 'Crossover' studies	7	2120	Risk Ratio (M‐H, Random, 95% CI)	0.85 [0.58, 1.23]