Fig. 3.

ATX mice display mild hypertension, carotid wall thickening, and stiffening. a Systolic (left), diastolic (middle), and pulse (right) pressures measured by Millar catheter in the ipsilateral carotid of sham- (n = 4) and TAC-WT (n = 7) and sham- (n = 4) and TAC-ATX (n = 5) mice. b Wall thickness (left) and compliance (right) of ipsilateral carotid arteries isolated from WT (n = 6–8) and ATX (n = 6) mice. Data are mean ± SEM *p < 0.05 vs. WT mice; ^$p < 0.05 vs. sham mice (within the corresponding genotype)