Fig. 1.

Left panel: Total distance moved by (a) male WT (n = 12) and Sod1KO (n = 10) mice, and (b) female WT (n = 12) and Sod1KO (n = 6) mice obtained by tracking animal movements during the 90-h experimental period. Data are averaged over hourly intervals during both the light and dark phases of the light-dark cycle. Dark horizontal lines represent the dark phase of the cycle. Data represent mean + SEM calculated for hourly intervals. Right panel: Summary of the total distance moved over the 90-h period by male (a) and female (b) WT and Sod1KO mice during light and dark cycles. Data represent mean ± SEM for each group. *p < 0.05