Figure 6.
Kaplan-Meier time-to-event analysis showing cessation of seizure-like behavior in rats challenged with a subcutaneous dosage of the VX surrogate nitrophenyl ethyl methylphosphonate (NEMP; 0.65 mg/kg) followed by 2-PAM or novel oximes alone or in combination with 2-PAM delivered intramuscularly in multisol at 0.146 mmoles/kg at time of initiation of seizure-like behavior (about 30 min post NIMP challenge). Hash marks indicate animal death. Data adapted from data in Chambers et al., 2016b.