Table 1:

Twenty four hour survival of male rats challenged with a lethal dosage of a sarin surrogate (nitrophenyl isopropyl methylphosphonate; NIMP; 0.6 mg/kg, subcutaneous) or a VX surrogate (nitrophenyl ethyl methylphosphonate; NEMP; 0.65 mg/kg, subcutaneous), with oxime (0.146 mmol/kg in multisol, intramuscular) and atropine (0.65 mg/kg, in saline, intramuscular) administered at time of initiation of seizure-like behavior, about 30 min post-organophosphate. Odds ratio is in comparison to 2-PAM alone.

Oxime	NIMP			NEMP
	Surv./ Trted.	%Surv.	Odds Ratio	Surv./ Trted.	%Surv.	Odds Ratio
None	0/20	0		0/20	0
2-PAM	8/20	40		6/20	30
1	13/20	65	2.8*	15/20	75	6.3*
15	12/20	60	2.3*	17/20	85	11.2*
20	11/20	55	1.8*	12/20	60	4.0*
55	6/20	30	0.6*	11/20	55	2.7*
62	11/20	55	1.8*	13/20	65	4.0*
1+ 2-PAM	11/15	73	4.1*	8/15	53	2.5*
15 + 2PAM	10/15	67	3.0*	15/15	100	69.1*
20 + 2-PAM	13/15	87	9.7*	8/15	53	2.5*
55 + 2-PAM	8/15	53	1.7*	14/15	93	21.6*
62 + 2-PAM	9/15	60	2.3*	14/15	93	21.6*

^*P<0.05. (Data from this experiment also shown in Figure 4.