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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Bone. 2019 Oct 31;130:115126. doi: 10.1016/j.bone.2019.115126

Figure 5:

Figure 5:

Age-related changes in bone matrix characteristics of BALB/c femoral diaphysis. Ct.TMD of the intact femoral mid-shaft (A) and notched femoral mid-shaft (B) was higher at 20-mo. than at 6-mo. Mature enzymatic (PYD) collagen crosslink was higher (C), while bound water was lower (D) with advanced age. A non-enzymatic collagen crosslink (PE) was also higher for aged mice than young adult mice (E). Cross-sectional area of the mid-shaft was only higher with age for female mice (F). 6-mo mice are represented by circles and 20-mo. mice are represented by squares. **p<0.01, ***p<0.001, ****p<0.0001 within male. #p<0.05, ##p<0.01, ###p<0.001 and ####p<0.0001 within female.