Table 2.
Genotype and allele frequencies of SOX2OT in RM patients and controls.
| Genotype/allele | RM (N = 570) | Controls (N = 578) | P valuea | OR (95% CI) | P value | Adjusted OR (95% CI) | P valueb |
|---|---|---|---|---|---|---|---|
| SOX2OT/rs9839776 C>T (HWE = 0.252) | |||||||
| CC | 361 (63.33) | 369 (63.84) | 1.00 | / | 1.00 | / | |
| CT | 182 (31.93) | 180 (31.14) | / | 1.351 (1.061-1.721) | 0.0146 | 1.357 (1.065-1.728) | 0.0134 |
| TT | 27 (4.74) | 29 (5.02) | / | 1.244 (0.726-2.133) | 0.4268 | 1.247 (0.727-2.139) | 0.422 |
| Additive | 0.9444 | 1.007 (0.826-1.228) | 0.9474 | 1.007 (0.826-1.228) | 0.9439 | ||
| Dominant | 209 (36.67) | 209 (36.16) | 0.8582 | 1.022 (0.804-1.300) | 0.8582 | 1.024 (0.805-1.303) | 0.8451 |
| Recessive | 543 (95.26) | 549 (94.98) | 0.8254 | 0.941 (0.550-1.611) | 0.8255 | 0.935 (0.546-1.601) | 0.8061 |
a χ 2 test for genotype distributions between recurrent miscarriage patients and controls. bAdjusted for age. RM: recurrent miscarriage.