Table 2.
Correlation coefficient of clinical characteristics associated with plasma valine concentration in the study individuals.
| Plasma valine | Plasma valine (age- and sex-adjusted) | |||
|---|---|---|---|---|
| r | p value | r | p value | |
| Age (year) | 0.008 | 0.963 | — | — |
| Sex (M/F) | 0.133 | 0.421 | — | — |
| BMI (kg/m2) | -0.225 | 0.168 | -0.210 | 0.212 |
| HbA1c (%, mmol/mol) | 0.231 | 0.156 | 0.273 | 0.103 |
| FPG (mmol/L) | 0.322 | 0.046 | 0.340 | 0.040 |
| 2hPG (mmol/L) | 0.277 | 0.088 | 0.301 | 0.071 |
| Insulin (mU/L) | -0.123 | 0.456 | -0.126 | 0.457 |
| HOMA-IR | -0.026 | 0.873 | -0.027 | 0.873 |
| HOMA-β | -0.279 | 0.085 | -0.299 | 0.073 |
| Total cholesterol (mmol/L) | 0.069 | 0.674 | 0.076 | 0.654 |
| Triglycerides (mmol/L) | 0.063 | 0.703 | 0.070 | 0.679 |
| HDL-C (mmol/L) | 0.019 | 0.907 | 0.002 | 0.989 |
| LDL-C (mmol/L) | 0.054 | 0.743 | 0.074 | 0.664 |
BMI, body mass index; FPG, fasting plasma glucose; 2hPG, 2-hour postprandial plasma glucose; HOMA-IR, homeostasis model assessment for insulin resistance; HOMA-β, homeostasis model assessment for beta-cell function; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. Correlations between valine concentration and clinical characteristics were analyzed by Pearson's analysis or an age- and sex-adjusted partial correlation test, while the correlation between valine concentration and sex was analyzed by Spearman's analysis.