Figure 6. Cumulative survival rate of patients with cholangiocarcinoma according to expression of p16INK4A and p21 alone (A and B) and in combination (C). Patients with high expression of either protein alone had a significantly longer survival than did those with low expression. Patients who had high expression of both of p16INK4A and p21 had significantly longer survival than those with low expression of one or both proteins.
