Figure 5. miRs affecting tumor growth and metastasis of pancreatic ductal adenocarcinoma xenografts. miR-96, -98-5p, -195, -202-5p, -615-5p, -663a and 4787-5p are down-regulated in pancreatic tumors in comparison to corresponding normal tissues. AKT2: Protein kinase β; DCLK1: doublecortin-like kinase 1; HERG1: human ether-a-go-go related gene product; MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4; TGFβ1: transforming growth factor β1; TGFβR1,2: transforming growth factor β receptor 1 and 2.