Figure 5. Invasiveness-network shows engagement of biological processes at a scale comparable to the numbers of biological processes engaged by the protein and gene diagnostic signatures. Numbers of biological processes reported here: invasiveness network (1,085 processes), diagnostic gene-signatures Mammaprint Dx (1,194 processes), OncoType Dx (1,103 processes), Invasiveness Gene Signature (1,140 processes), PAM50 (1,353 processes), and proteomics signatures of invasive cells (152 proteins; 1,076 processes), triple-negative breast cancer (11 proteins; 559 processes), grading signature (49 proteins; 954 processes), and aggressiveness signature (44 proteins; 1,203 processes). Note engagement of large number of biological processes by the signatures, identified by systemic analysis (see file of the networks, which is deposited ta BioModels at ebi.ac.uk, identifier MODEL1904060001).