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. 2019 Dec 1;2019(12):CD003006. doi: 10.1002/14651858.CD003006.pub4

Aouad 2001.

Methods Randomization: yes
Participant blinding: yes
Provider blinding: no
Assessor blinding: yes
Dropouts: 0
Participants Country: Lebanon
ASA: I and II
Gender: women
Mean age: 31 (SD 5) years
Caesarean section
Surgical positioning: supine
Number of participants: 200
Interventions Drug 1: 5% lido, hyperbaric, fixed dose (1.5 mL)
Drug 2: 0.75% bupi, hyperbaric, fixed dose (1.6 mL)
Needle: 25 G, pencil‐point
Outcomes TNS at 1 day
Back pain
Notes Follow‐up duration: 1.3 days
Follow‐up method: telephone contact
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "patients were allocated randomly by sealed envelope…"
Comment: did not specify the method of randomization (referring to a random number table, computer‐generated random number sequence, tossing coin, etc.).
Allocation concealment (selection bias) Unclear risk Quote: "patients were allocated randomly by sealed envelope…"
Comment: did not specify allocation by sequentially numbered, sealed, opaque envelopes.
Participant blinding (performance bias and detection bias) Low risk Quote: "patients were blinded as to the spinal anesthetic used."
Provider blinding (performance bias) High risk Quote: "the anesthesiologist who administered the spinal anesthetic and collected the data on sensory and motor blockade was not blinded as to the study groups."
Assessor blinding (detection bias) Low risk Quote: "all patients were interviewed… by an anesthesiologist who was unaware of the local anesthetic given."
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 200 participants enrolled. Results reported for 200 participants.
Selective reporting (reporting bias) Unclear risk Study protocol not available.