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. 2019 Dec 1;2019(12):CD003006. doi: 10.1002/14651858.CD003006.pub4

Hodgson 2000.

Methods Randomization: yes
Participant blinding: yes
Provider blinding: no
Assessor blinding: yes
Dropouts: 0
Participants Country: USA
ASA: I and II
Gender: men and women
Mean age: lido: 49 (SD 12); pro: 49 (SD 12) years
Procedures: arthroscopy
Ambulatory surgery: yes
Surgical positioning: supine
Number of participants: 70
Interventions Drug 1: 5% lido, hyperbaric, fixed dose (1 mL)
Drug 2: 5% pro, hyperbaric, fixed dose (2 mL)
Needle: 24 and 25 G, pencil‐point
Outcomes TNS at 1 day
Notes Follow‐up duration: 3 days
Follow‐up method: telephone contact
TNS therapy: unclear
TNS resolution: 48 hours
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "randomization was accomplished by random selection of blank, closed envelopes assigned by a computer‐generated scheme to lidocaine or procaine by a numerical code which remained unbroken until data collection and assessment of all patients was complete."
Allocation concealment (selection bias) Low risk Quote: "randomization was accomplished by random selection of blank, closed envelopes assigned by a computer‐generated scheme to lidocaine or procaine by a numerical code which remained unbroken until data collection and assessment of all patients was complete."
Participant blinding (performance bias and detection bias) Low risk Quote: "the patient remained blinded to the study drug."
Provider blinding (performance bias) High risk Quote: "…side effects…were managed intraoperatively by the managing anesthesia team, which was not blinded to the spinal drug."
Assessor blinding (detection bias) Low risk Quote: "patients were contacted…by a single anesthesiologist blinded to the agent that the patient had received."
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Randomized 70 participants, results reported on 70 participants.
Selective reporting (reporting bias) Unclear risk Study protocol not available.