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. 2019 Oct 30;10(12):2289–2299. doi: 10.1111/1759-7714.13226

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© 2019 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Glutamine transporter and glutaminase mRNA expression in adeno‐ versus squamous cell non‐small cell lung cancer. Expression of glutamine transporter SLC1A5 mRNA (a), glutaminase mRNA and (b) glutaminase 2 mRNA (c) is higher in adenocarcinomas relative to squamous cell carcinomas. Levels are expressed as ratios of HPRT. (d,e) Immunofluorescent images of adeno NSCLCs showing SLC1A5 (d) and GLS2 (e) expression. Red, SLC1A5 or GLS2; green, vessels; magnification 100x; scale bars represent 100 μm. GLS, glutaminase; SLC1A5, solute‐linked carrier family A1 member 5.